Medicinal Chemistry (Custom Synthesis/Contract Research Manufacturing Services)
GENSEN is focused on partnering with clients across the entire chemical development process starting with the mgs required for primary assays to the multiple kgs required for clinical trials.
We currently work with over 10 clients across the globe and have delivered over 23 projects in the last 2 year. We are an integrated chemistry facility with discovery chemistry, process research and analytical support staff.
We have labs and manufacturing facilities (kilo lab) capable of producing any drug molecule or intermediate from mg to 5 kg scale.
Our team of highly qualified and specialized chemists assure timely delivery of all our services and are committed to customer responsiveness and satisfaction.
For the new drugs under development, supply of required new and advanced chemical intermediates is very important factor. The expertise of our highly experienced team allows us to offer a flexible Custom Synthesis Service for organic compounds of all types. We offer competitive prices and delivery times of products made to your specifications. We can work with your process, a literature process, or we can develop a process ourselves, as appropriate.
We have the capability of custom synthesizing a wide range of intermediates, reference compounds, building blocks depending on the requirements of the customers.
Chemistry Specialization: (not limited to…)
Amino acids and peptides
Carbohydrates
Nucleosides
Terpenes
Alkaloids
Fatty acids and Prostaglandins
Heterocycles
Steroids and Vitamin-D Chemistry
Conjugated Oligomers
Organo Metallics
Fine Chemicals including Chiral Chemistry and Aromatics
Polyethylene glycol derivatives
Combinatorial Chemistry
Solid Phase synthesis
Reaction capabilities: (not limited to…)
Alkylation
Asymmetric synthesis
Halogenation
Ketalization
Oxidation and Reduction
Grignard Reaction
Organolithium reaction
Hydrogenation
Cyanation
Epoxidation
Ozonization
Photocyclic Reaction
Development / Scale Up / Manufacturing of Intermediates and API (Active Pharmaceutical Ingredient)
Development and technology transfer of intermediates (from mg level to 1-5 kg level)
Development and technology transfer of API (from mg level to 1-5 kg level)
Manufacturing of intermediates and APIs (mg levels to 50 kg)
Development and manugacturing of Fine Chemicals (mg levels to 5 kg)
Patent Evaluation Report : API and Formulation
Patent Drafting for API and Formulation
Patent Filing US/EU and Rest of the world
Non-infringing process clearance : API & Formulation
Regulatory Affairs Services (US DMF/CTD/Dossier)
Review and Compilation of US Drug Master File (USDMF)
Review and Compilation Common Technical Document (CTD)
Review and Compilation of Formulation Dossiers
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